david71 wrote:... The pen stops being recognised by the tablet, all touch gestures are recognised and to get the pen working again I have to restart the Mac then within 10 mins the pen looses connection again.
I'm sorry to hear that you're not out of the woods yet David. I know the feeling far too well.
But I must say that I haven't had any lost connectivity with the latest 6.3.19-10 driver running macOS 10.12.2 and an Intous PTH-651 connected by USB-wire over a days activity. Are you using bluetooth to connect the tablet? Frankly I don't see the point using battery powered wireless technology in many cases. However I have noticed a very long (about 20 to 30 s) wake-up time for my tablet at work running OS X 10.11 and an earlier Wacom driver after waking the Mac from standby.
After about three and a half years I can finally say; thank you Wacom! In fact this 6.3.19-10 driver works so well for me I'm going to stick with it in foreseeable future.
PS. Neither will I update to Adobe CC 2017 which is, at least over time, bound to mess things up.